Advanced Medical Development

Staff

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Chief
Haruyasu
Murakami, M.D., Ph.D.

(Also Serving as Manager, Chemotherapy Center)

Deputy Chief Kazushige Wakuda, M.D., Ph.D.
(Also Serving as Senior Staff, Div. of Thoracic Oncology)

Masashi Niwakawa,M.D., Ph.D.
(Also Serving as Deputy Director and Chief, Div. of Urology)

Shusuke Yoshikawa, M.D.
(Also Serving as Chief, Div. of Dermatology)

Yuji Ishida, M.D.
(Also Serving as Deputy Director and Chief, Div. of Pediatrics)

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Takeshi Aramaki, M.D.
(Also Serving as Chief, Clinical Development, Div. of Interventional Radiology)

Yusuke Onozawa,
M.D.

(Also Serving as Chief, Div. of Clinical Oncology)

Nahomi Tokudome, M.D., Ph.D.
(Also Serving as Chief, Div. of Breast Oncology)

Satoshi Hamauchi, M.D.
(Also Serving as Senior Staff, Div. of Gastrointestinal Oncology)

Kentaro Yamazaki, M.D., Ph.D.
(Also Serving as Chief, Div. of Gastrointestinal Oncology)

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Tomoya Yokota, M.D., Ph.D.
(Also Serving as Senior Staff, Div. of Gastrointestinal Oncology)

Junji Wasa, M.D., Ph.D.
(Also Serving as Senior Staff, Div. of Orthopedic Oncology)

Munetaka Takekuma, M.D., Ph.D.
(Also Serving as Chief, Div. of Gynecology)

Akiko Shibatani (Furusawa), M.D., Ph.D. 
(Also Serving as Senior Staff, Div. of Gynecology)

Ryo Ko, M.D., Ph.D.
(Also Serving as Senior Staff, Div. of Thoracic Oncology)

Features and Therapeutic Strategy of the Division at the SCC

This is a new clinical division launched in April, 2024. It specializes in early clinical development for anti-malignant tumor (anti-cancer) drugs. The phase I clinical trial is the very first step for a clinical development of a new anti-cancer drug. That’s when safety as well as efficacy of the drug are evaluated, and optimal dose and administration method are studied and discussed. At this early stage of the clinical development, the subject is often targeted to a wide range of malignant tumors, rather than a specific type of tumor or an organ, which makes it more sensible to have a cross-organ research system than otherwise. In addition, as a newly-developed anti-cancer drug may have an action mechanism different from conventional anti-cancer drugs, side effect management will also be beyond the scope of conventional ones. At the SCC, we have already had interprofessional collaborations among doctors and nurses at various clinical divisions, pharmacists, clinical test coordinators, etc. for the early clinical developments including the phase I clinical trials. Now that the Division of Advanced Medical Development has been established, a ward dedicated for the treatment management is prepared, the medical staff equipped with expertism and ample experiences in the field is stationed there, and the developments are being carried out much safer and faster than before.

In recent years, cancer genome profiling analysis has been clinically introduced, and new therapies focusing on specific gene abnormalities have been prominently developed ever since. At the same time, the number of therapies with the efficacies proven at the early stages of clinical developments has been increasing. This division works closely together with the Genomic Medicine Support Office to promote early clinical development of an effective new anti-cancer drug based on the results of cancer genome profiling analyses, aiming at the benefits of cancer patients by delivering it as fast as possible.

Fields of Expertise, Professional Memberships and Credentials

Haruyasu Murakami, M.D., Ph.D., Chief, Also Serving as Manager, Chemotherapy Center,

Fields of Expertise

chemotherapy for lung cancer
clinical oncology

Professional Memberships and Credentials

Certified Physician and Specialist, the Japanese Society of Internal Medicine

The Japanese Society of Medical Oncology

Specialist and Supervisory Doctor Certified by the Japanese Respiratory Society

The Japanese Cancer Association
The Japan Lung Cancer Society
The Japan Society of Clinical Oncology
General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy
The American Society of Clinical Oncology (ASCO)

Kazushige Wakuda, M.D., Ph.D., Deputy Chief, Also Serving as Senior Staff, Div. of Thoracic Oncology

Fields of Expertise

respiratory medicine

Professional Memberships and Credentials

Certified Physician and Specialist, the Japanese Society of Internal Medicine

Specialist Certified by the Japanese Respiratory Society
Specialist Certified by the Japan Society for Respiratory Endoscopy
The Japanese Society of Medical Oncology
The Japan Lung Cancer Society

General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy

Masashi Niwakawa, M.D., Ph.D., Also Serving as Deputy Director, and Chief, Div. of Urology

Fields of Expertise

diagnosis and treatment for malignant tumor in urological organs

Professional Memberships and Credentials

The Japanese Society of Medical Oncology

Shusuke Yoshikawa, M.D., Also Serving as Chief, Div. of Dermatology

Fields of Expertise

malignant skin tumor
dermatologic surgery
drug therapy

Professional Memberships and Credentials

Specialist Certified by the Japanese Dermatological Association
Supervisory Specialist of the Malignant Skin Tumor

General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy

Commissioner, the Japanese Skin Cancer Society
The Japan Society of Clinical Oncology
The Japanese Society of Medical Oncology
The Japanese Association of Supportive Care in Cancer

Yuji Ishida, M.D., Ph.D., Also Serving as Deputy Director and Chief, Div. of Pediatrics

Fields of Expertise

pediatric cancer
support for cancer patient and his/her family

Professional Memberships and Credentials

Specialist Certified by the Japan Pediatric Society

Hematologist Certified by the Japanese Society of Hematology

The Japanese Society of Pediatric Hematology/Oncology
The Japan Society for Neuro-Oncology
The Japanese Society for Transplantation and Cellular Therapy
International Member of the Children’s Oncology Group, U.S.A.

Takeshi Aramaki, M.D., Ph.D., Also Serving as Chief, Clinical Development, Div. of Interventional Radiology

Fields of Expertise

IVR procedures

Professional Memberships and Credentials

Certified Radiologist and Supervisory Doctor, Representative, the Japanese Society of Interventional Radiology

Certified Radiologist, the Japan Radiological Society

Facilitator for the IVR Study Group in Central Japan, the Japanese Society of Interventional Radiology

Facilitator, the Palliative IVR Study Group
Representing Facilitator, the Shizuoka IVR Forum

Facilitator, the Japan Association for Percutaneous Trans-Esophageal Gastro-Tubing

Organizer, the Japanese Society of Implantable Port Assisted Treatment

Fellow, the Cardiovascular and Interventional Radiology Society of Europe

Yusuke Onozawa, M.D., Also Serving as Chief, Div. of Clinical Oncology

Fields of Expertise

chemotherapy for gastroenterological cancer (i.e., gastrointestinal lymphoma, gastrointestinalstromal tumor (GIST))

chemotherapy for cancer in head and neck region

Professional Memberships and Credentials

Certified Specialist for Cancer Chemotherapy and Supervisory Doctor for Specialist in Cancer Chemotherapy, Councilor, and Certified Interim Supervisory Doctor, the Japanese Society of Medical Oncology

General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy

Certified Physician, Specialist and Supervisory Doctor, the Japanese Society of Internal Medicine

Specialist Certified by the Japanese Society of Gastroenterology

The Japan Society of Clinical Oncology
The American Society of Clinical Oncology (ASCO)
The Japanese Society of Hematology
The Japan Society for Head and Neck Cancer
The Japan Society for Hematopoietic Cell Transplantation

The Japan Society of Transfusion Medicine and Cell Therapy

The Japan Gastroenterological Endoscopy Society

Nahomi Tokudome, M.D., Ph.D., Also Serving as Chief, Div. of Breast Oncology

Fields of Expertise

drug treatment for breast cancer, development of new drugs, cancer genome medicine, quality control of clinical studies, translational research

Professional Memberships and Credentials

Certified Specialist for Cancer Drug Therapy and Supervisory Doctor, Councilor, the Japanese Society of Medical Oncology

Specialist Certified by the Japanese Breast Cancer Society

Registered Medical Practitioner Certified by the Japan Surgical Society

General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy

Specialist for Mammography-interpretation at the Breast Cancer Screenings Certified by the Japan Central Organization on Quality Assurance of Breast Cancer Screening

The Japanese Society of Internal Medicine
The Japanese Society for Hereditary Tumors
The Japan Society of Clinical Oncology

Satoshi Hamauchi, M.D., Also Serving as Senior Staff, Div. of Gastrointestinal Oncology

Fields of Expertise

chemotherapy for cancers in the head and neck region and the digestive system

Professional Memberships and Credentials

Certified Physician, the Japanese Society of Internal Medicine
Specialist Certified by the Japanese Society of Gastroenterology

Cancer Chemotherapy Specialist Certified by the Japanese Society of Medical Oncology

Kentaro Yamazaki, M.D., Ph.D., Also Serving as Chief, Div. of Gastrointestinal Oncology

Fields of Expertise

chemotherapy for gastrointestinal cancer (colorectal cancer)

Professional Memberships and Credentials

Certified Physician, the Japanese Society of Internal Medicine
The Japan Gastroenterological Endoscopy Society
The Japan Society of Clinical Oncology
The Japanese Society of Gastroenterology
The Japanese Society of Medical Oncology
The Japan Society of Coloproctology
The Japanese Association for Molecular Target Therapy of Cancer
The American Society of Clinical Oncology (ASCO)
The European Society for Clinical Oncology (ESMO)

Tomoya Yokota, M.D., Ph.D., Also Serving as Senior Staff, Div. of Gastrointestinal Oncology

Fields of Expertise

chemotherapy for cancers in the head and neck region and the digestive system
molecular biology

Professional Memberships and Credentials

Certified Physician, the Japanese Society of Internal Medicine

Cancer Chemotherapy Specialist and Supervisory Doctor Certified by the Japanese Society of Medical Oncology

The Japanese Cancer Association
The Japan Society for Head and Neck Cancer
The Japan Esophageal Society
The Japan Society of Clinical Oncology
The Japanese Society of Gastroenterology
The Japanese Association of Supportive Care in Cancer
The American Society of Clinical Oncology (ASCO)
The European Society for Medical Oncology (ESMO)

Junji Wasa, M.D., Ph.D., Also Serving as Senior Staff, Div. of Orthopedic Oncology

Fields of Expertise

tumors in bones and soft tissues

Professional Memberships and Credentials

Specialist and Oncologist for Bones and Soft Tissues Certified by the Japanese Orthopaedic Association

General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy

The Central Japan Association of Orthopaedic Surgery & Traumatology

The Japan Society of Clinical Oncology
The Japanese Cancer Association

Munetaka Takekuma, M.D., Ph.D., Also Serving as Chief, Div. of Gynecology

Fields of Expertise

gynecological oncology

Professional Memberships and Credentials

Specialist and Supervisory Doctor Certified by the Japan Society of Obstetrics and Gynecology

Certified Specialist and Supervisory Doctor, Commissioner, Councilor, Vice-Chairman of the Editorial Committee for Revising the Uterine Corpus Cancer Therapy Guidelines, Editorial Committee Member for Revising the Uterine Cervical Cancer Therapy Guidelines, Editorial Committee Member for Revising the Ovarian Cancer Therapy Guidelines, Working Group Member per Organ for the Particle-Beam Radiation Therapy Assessment, the Japan Society of Gynecologic Oncology

General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy

Cytodiagnosis Specialist and Commissioner for the Shizuoka Branch Office, the Japanese Society of Clinical Cytology

Working Group Member for Revising the Guidelines for Proper Use of G-CSF, the Japan Society of Clinical Oncology

Working Group Member for Revising the Cancer Immunotherapy Guidelines, the Japanese Society of Medical Oncology

The Japan Society of Gynecological and Obstetrical Surgery

The Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy

Educational Seminar Lecturer, the Japan Organization of Hereditary Breast and Ovarian Cancer (JOHBOC)

Commissioner, Chairman of the Cervical Cancer Committee, GICG Board Member, the Japanese Gynecologic Oncology Group (JGOG)

Representative Member of the Gynecological Oncology Group, Member for the International Testing Cooperation, the Japan Clinical Oncology Group (JCOG)

Researcher, the National Cancer Institute (USA)
Associate Editor, Gynecologic Oncology Research and Practice
Clinical Associate Professor, Hamamatsu University School of Medicine

Akiko Shibatani (Furusawa), M.D., Ph.D., Also Serving as Senior Staff, Div. of Gynecology

Fields of Expertise

gynecological oncology

Professional Memberships and Credentials

Specialist and Supervisory Doctor Certified by the Japan Society of Obstetrics and Gynecology

Certified Specialist and Supervisory Doctor, Editorial Committee Member for Revising the Treatment Guidelines for Uterine Corpus Cancer, the Japan Society of Gynecologic Oncology

General Clinical Oncologist Certified by the Japanese Board of Cancer Therapy

The Japan Society of Clinical Oncology
The Japanese Cancer Association

The Japan Society of Gynecologic and Obstetric Endoscopy and Minimally Invasive Therapy

Specialist Certified by the Japanese Society for Hereditary Tumors

Committee Member for Uterine Cervical Cancer, Qualification Committee Member for Clinical Trial and Ethical Regulations, the Japanese Gynecologic Oncology Group (JGOG)

Ryo Ko, M.D., Ph.D., Also Serving as Senior Staff, Div. of Thoracic Oncology

Fields of Expertise

respiratory medicine

Professional Memberships and Credentials

Certified Physician, the Japanese Society of Internal Medicine
The Japanese Respiratory Society
The Japan Lung Cancer Society
The Japanese Society of Medical Oncology

Shizuoka Cancer Center

Shizuoka Cancer Center